I've only tried pot. Don't really want to try anything harder cause I think the risk of brain damage and/or addiction is too high. The pot wasn't that special, I felt all the classic effects - laughing, thirst, hunger. one time I really got stoned like an idiot and it made me feel thirsty for weeks after, literally. I never smoked again after that. I don't like taking medical drugs, either. They make me feel very dehydrated and I get a distinct feeling that they lower my energy. For the last 4-5 years I have absolutely refused to take any antibiotics cause they are very aggressive, they hurt your digestive organs, they don't boost your immune system at all and the infection which you defeat with antibiotics can easily come back. But doctors won't really tell you that.