Oh yes. Perfectionism in relationships is something I once struggled with greatly. For myself, but namely the other party, it was a source of oppressiveness and pettiness when I was in my late teens (18/19), and caused tsunami waves in the relationships over what were little waves beforehand. In hindsight I am quite embarrassed at how I once behaved - but then again they were also immature in many ways. Of course an aim for betterment and to address issues without letting them fester is necessary, but that fascist-like perfectionism which holds those in the relationship (romantic, platonic, familial) to a saintly standard in which expectations are impossibly high, and where dependency issues are often accompanied, has by no means been anything but a nuisance. It really is a kill-joy and can guilt-trip the other party, and take away from personal freedom for each to have some form of independence without the need to be hand-in-hand or watched like a hawk.
Nowadays, through mistakes, realising truly and really that no one's perfect, and through self-knowledge of my own weaknesses and capacity for selfishness etc., I've learnt to place no expectations on others and to adopt the following moto: "Compromise in all things that don't matter, for the sake of the things which do matter." How much more enjoyable and freeing my relationships have been ever since! Not that I've worked it all out, but still, things are better now that I've dropped the perfectionism in regards to others, and have realigned it to be a perfectionism that seeks to let others be free and to simply love as the best I can - yet it's not a rigid perfectionism so that I do not beat myself up over characteristically human mistakes. So I guess just as perfectionism can be a nightmare in relationships, it can be really good, provided it's not of the oppressive kind.