I disagree that all are created equal; and especially when application/achievement is taken into account, all are far from being equal .
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One person aces a test after studying all week. Another gets a C without studying, but is on the football team.
Yet another couldn't get a C if they tried. May we establish what equality means?
This phrase simply means that no man is the master of any other man. Each has the right to live their life as they choose and not as another chooses.
Why do all men need to be equal, why should we work towards this?
We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the Pursuit of Happiness. That to secure these rights, Governments are instituted among Men, deriving their just powers from the consent of the governed
The reason that people ought to be treated fairly and equally is not that they aren't different from one another. Rather, it's that they have agency, positive and negative experiences, preferences, and feelings. If we want to describe something as being kindly, or as diminishing suffering, we use the word "humane", which simply means "like a human". That says a lot about us.
Why do all men need to be equal, why should we work towards this?
Also what this boils down to is "why do we treat everyone fairly?"
People answer this question in various ways, such as "we're all humans" or "everyone has feelings" but almost always they point to one unifying common denominator. For example this skeptic says here http://bigthink.com/the-proverbial-skeptic/all-men-are-created-equal-really
So this person says that everyone is not the same, yet seems to point out a thing that is the same about everyone. That common denominator is the point of equality.