Weird. Some examples:
Positive Connotation
-"Omg you're so weird, lol"
-"STOPPP weirdo xD"
- "This is my weird friend, ____"
Negative Connotation
-"Yo, you weird, girl"
-"Bunch of weirdos, ugh"
-"Why are you being so weird?!"
It's kind of universal for me, good and bad.